The impact of different drugs on relaxation or contraction of the endothelium or vascular smooth muscles can be investigated using isolated tissue bath protocols.
This application note includes:
- - An introduction about the crucial role of the endothelium
- - A focus on recent studies where tissue baths were used to investigate cardiovascular diseases: Atherosclerosis, hypertension, heart failure, diabetes and metabolic syndrome
- - A protocol explaining how to set an experiment to study rodents aorta rings on tissue bath