The most popular allergens used experimentally today are OVA and HDM, based on their ability to produce a Th-2 mediated inflammatory response.

 

Asthma+overview

This summary document covers: 

  • model development protocol
  • the physiological response to OVA and HDM 
  • Acute versus chronic experimental models 
  • summary of OVA versus HDM murine models 
    • antigen characteristics
    • acute vs chronic
    • immunological response
    • AHR response

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