About the Presentation
This comprehensive 22-page presentation explores two specific case studies using the NPFE (Negative Pressure Forced Expiration) extension for the flexiVent FX, to complement classical and detailed mechanics outcomes with clinically-relevant measures of forced expiration in various disease models.
Presentation sections:
- About the NPFE Extension
- Important Considerations for FEV
- Equipment Diagrams
- The FEV Manoeuvre
- NPFE Outcomes
- Parameters and Pertubations
- Case Study 1: Lung Function in Mouse Fibrosis Models
- Model Development
- Flow-Volume Curves
- FEV and FVS Results
- Case Study 2: FEV Measurements in Mouse Models of Obstructive and Resistive Lung Diseases
- The Quick-Prime Manoeuvre
- Deep Inflation and PV Loop
- FOT Measurements
- Flow-Volume Curves: Fibrosis, Emphysema
- FEV Results
- Airway Hyperresponsiveness
- Flow-Volume Curves: Naive, ALI, Asthma
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