The Morty Lab at the Max Planck Institute for Heart and Lung Research in Germany integrated the flexiVent & Whole Body Plethysmography into their neonate research to measure lung mechanics in Bronchopulmonary Dysplasia (BPD) pups.

This presentation by Dr. David Surate Solaligue & Dr. Claudio Nardiello was presented during SCIREQ’s annual breakfast event during ATS 2019 outlines some of the challenges faced (and overcome) when measuring mouse pups for BPD.

  • Baseline values, anaesthesia and tracheostomy considerations when using the flexiVent to assess lung mechanics
  • Noise, temperature, and exposure conditions when using plethysmography to assess breathing parameters

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About the Morty Lab

The Morty Lab has two major research themes, both of which relate directly to adult and neonatal critical care medicine. They are currently exploring what causes premature infants to develop BPD when they are ventilated, and new ways to clinically manage this complex and important clinical problem encountered in the neonatal intensive care unit.

Abstract

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